Qiuyun Fan, Ph.D

时间： 2015-12-18 12:30 - 14:30

地点： Room 1113, Wang Kezhen Building

Diffusion MRI (dMRI) probes the propensity of water diffusion in the anisotropic environment to gain microstructural information of tissue properties. One of the major goals of the NIH Blueprint Human Connectome Project (HCP) was to map the fibrous connections in the brain using diffusion tractography. Enabled by the 300mT/m gradient on the MGH-USC Connectome scanner, we demonstrated increasing b-value (i.e., the degree of diffusion weighting) improvedthe delineation of the finer details of complex white matter structures, such as crossing fibers, which is prevalent in cerebral white matter.Cerebral cortex, however, is rich in gyral folding. The characteristics of radial diffusion in cortex rely upon the use of high spatial resolution to be resolved. To improve the cortico-cortical connectivity measurement using diffusion tractography, we developed a method to hybrid the benefits from high b-value and high resolution diffusion MRI. In summary, this talk will discuss our experience of the high b-value diffusion MRI as part of the NIH HCP project, and introduce the method of HIghb-value and high Resolution Integrated Diffusion (HIBRID) MRI, along with some of the efforts being made in our group in pushing to the limit of imaging resolution of dMRI.

2015-12-18

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2015-12-18